Par investigadores
J.J. Hernández Morante, C. Gómez Martínez, J.M. Morillas-RuizNutrients. 2019;11(1). pii: E102. doi: 10.3390/nu11010102 As the population ages, the need for specialised geriatric care will increase immensely, and consequently, the need for specialised services for the care of these people will increase accordingly. From a nutritional point of view, to control or balance the nutritional status of residents will be essential in order to prevent sarcopenia and, consequently, frailty development. |
L. Lorenzo-López, R. López-López, A. Maseda, et al.Maturitas. 2019;119:54-60 Greater understanding of changes in the degree of frailty is important for clarifying the natural history of frailty and may help clinical decision-making regarding preventive interventions. The objectives of this study were to explore natural frailty transition rates at 1-year follow-up and to identify the main determinants of such transitions. |
Y. Lu, L.G. Karagounis, T.P. Ng, et al.J Gerontol A Biol Sci Med Sci. 2019 Jan 8. doi: 10.1093/gerona/glz001. [Epub ahead of print] The present cross-sectional study characterized the nutritional and metabolic profile of sarcopenia through an extensive exploration of a wide array of blood biomarkers related to muscle protein metabolism and transcriptomic signatures in community-dwelling elderly. |
A. Picca, R. Calvani, C. Leeuwenburgh, et al.Expert Opin Ther Targets. 2019;23(2):153-160 We discuss the evidence that points to mitochondrial dysfunction having a causative role in sarcopenia and the mechanisms involved in the accumulation of damaged mitochondria in the aged muscle. We also discuss the effects of physical exercise on mitochondrial quality control and muscle health in advanced age. |
H. Arrieta, G. Hervás, C. Rezola-Pardo, et al.Gerontology. 2018 Nov 21:1-11. doi: 10.1159/000494137. [Epub ahead of print] The aim is to determine the association of serum myostatin concentration with body composition, physical fitness, physical activity level, and frailty in long-term nursing home residents. We also aimed to ascertain the effect of an exercise program on myostatin levels. |
C. Mast, D. Dardevet, I. PapetNutr Res Rev. 2018;31(2):179-192 The present review provides the rationale for the potential pro-sarcopenic effect of paracetamol (acetaminophen; APAP) then recent results concerning the effect of chronic APAP treatment on muscle mass and metabolism are discussed. |



