Dla naukowców

Zespół słabości jako predyktor złamań w grupie starszych osób zamieszkujących własne gospodarstwa domowe: przegląd systematyczny i meta-analiza

G. Kojima

Bone. 2016;90:116-122

Przegląd systematyczny i meta-analiza wykazały, że osoby starsze mieszkające w społeczeństwie, spełniające kryteria zespołu słabości (frailty) oraz będące w grupie ryzyka rozwoju zespołu słabości (tzw. prefrailty) mają istotnie wyższe ryzyko złamań.

Serum markers of inflammation and oxidative stress in sarcopenia

B. Can, O. Kara, M.C. Kizilarslanoglu, et al.

Aging Clin Exp Res. 2017;29(4):745-752

The aim of the study was to evaluate the relationship between sarcopenia and biomarkers that may be involved in its pathogenesis and hence allow early detection. The present study demonstrated an association of sarcopenia with inflammatory markers CRP, erythrocyte sedimentation rate and adiponectin.

Physical Activity Performed in the Evening Increases the Overnight Muscle Protein Synthetic Response to Presleep Protein Ingestion in Older Men

A.M. Holwerda, I.W. Kouw, J. Trommelen, et al.

J Nutr. 2016;146(7):1307-14

The present study assessed whether physical activity performed in the evening can augment the overnight muscle protein synthetic response to presleep protein ingestion in older men. Physical activity performed in the evening augments the overnight muscle protein synthetic response to presleep protein ingestion and allows more of the ingested protein-derived amino acids to be used for de novo muscle protein synthesis during overnight sleep in older men.

Effect of dietary n-3 PUFA supplementation on the muscle transcriptome in older adults

J. Yoshino, G.I. Smith, S.C. Kelly, et al.

Physiol Rep. 2016;4(11). pii: e12785

In this study, we used muscle biopsy samples collected during a recently completed randomized controlled trial that found that n-3 PUFA therapy increased muscle mass and function in older adults to provide a comprehensive assessment of the effect of n-3 PUFA therapy on the skeletal muscle gene expression profile in these people. Data obtained suggest that n-3 PUFA therapy results in small but coordinated changes in the muscle transcriptome that may help explain the n-3 PUFA-induced improvements in muscle mass and function.

Successful Aging and Frailty: Opposite Sides of the Same Coin?

J. Woo, J. Leung and T. Zhang

J Am Med Dir Assoc. 2016;17(9):797-801

This study explore the hypothesis that frailty and successful aging are two sides of the same coin and that walking speed may be an objective indicator of successful aging. Fast walkers had better self-rated health, lower prevalence of stroke, hypertension, cataracts, osteoporosis, and impaired cognitive function. They were more likely to be current alcohol users, more physically active, consumed more vegetables, had better physical component of health-related quality of life, and received more education. They also had lower body mass index, percentage whole body fat as well as appendicular fat, and higher appendicular muscle mass index.

Associations of Computed Tomography-Based Trunk Muscle Size and Density With Balance and Falls in Older Adults

D.E. Anderson, E. Quinn, E. Parker, et al.

J Gerontol A Biol Sci Med Sci. 2016;71(6):811-6

Aging is associated with significant declines in muscle size and density, but associations of trunk muscle size and density with balance and falls in older adults have not been previously examined. Results suggest that higher muscle density was associated with reduced postural sway, particularly sway velocities, in both men and women, and better Short Physical Performance Battery score in women, but was not associated with falls.

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